Planta Medica 1990-02-01

Search for "in vitro" antiviral activity of a new isoflavonic glycoside from Ulex europaeus.

D J De Rodriguez, J Chulia, C M Simões, M Amoros, A M Mariotte, L Girre

Index: Planta Med. 56(1) , 59-62, (1990)

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Abstract

Extracts from Ulex europaeus L. (Fabaceae) were tested for antiviral activity against HSV-1 and poliovirus. It was found that the n-butanolic extract significantly inhibited the replication of these viruses, as shown by inhibition of cytophathic effects and reduction of plaques; the extract has neither a prophylactic nor a virucidal activity. From this extract has been isolated and identified by chromatographic, chemical, and spectroscopic methods, the 5-O-methylgenistein 7-O-beta D-glucopyranoside. This isoflavonic glycoside has not been previously described and it is responsible at least partially for the antiviral activity.