Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology 1997-10-01

Bioelectrical activity of brain in Rana tigrina (Daudin) in response to phosalone poisoning.

K Balasandaram, K Ramalingam, V R Selvarajan

Index: Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. 118(2) , 229-31, (1997)

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Abstract

An acute dose of phosalone, intraperitoneally injected to Rana tigrina alters the bioelectrical activity of the brain. The frequency levels of delta, theta, alpha, and beta waves remained similar in both control and experimental groups, while the amplitude of the waves was significantly decreased by 40 to 60% in the latter group. The total work done (TWD) was also significantly reduced. The above disturbance in the brain electrical activity may have correlation to the inhibition of cation-linked ATPase, as well as the cholinesterase activity.