Journal of Natural Products 1992-08-01

Vasoconstrictor activity of 8-O-acetylharpagide from Ajuga reptans.

M C Breschi, E Martinotti, S Catalano, G Flamini, I Morelli, A M Pagni

Index: J. Nat. Prod. 55(8) , 1145-8, (1992)

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Abstract

The traditional therapeutic indications for the use of Ajuga reptans (Labiatae) have been investigated. The H2O-soluble part of a crude and partially purified MeOH extract and two isolated iridoids (8-O-acetylharpagide and harpagide), were tested for a biological activity on isolated smooth muscle preparations from guinea pig.