Journal of Bioscience and Bioengineering 2011-01-01

Optical resolution of n-butyl D- and L-lactates using immobilized lipase catalyst.

Hitomi Ohara, Masafumi Yamamoto, Akihisa Onogi, Koichi Hirao, Shiro Kobayashi

Index: J. Biosci. Bioeng. 111(1) , 19-21, (2011)

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Abstract

n-Butyl D- and L-lactates (BuDLa and BuLLa) were incubated with immobilized lipase. (1)H-NMR showed that BuDLa reacted to oligomers, while BuLLa did not react. A mixture containing 90.4% of BuLLa and 9.6% of BuDLa was incubated with the enzyme for 72 h, then distilled. The purity of BuLLa increased to 98.6%.Copyright © 2010. Published by Elsevier B.V.