Journal of Medicinal Chemistry 2008-05-08

Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A.

Gavin Carr, Marco K W Chung, A Grant Mauk, Raymond J Andersen

Index: J. Med. Chem. 51 , 2634-7, (2008)

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Abstract

Synthetic analogues of the sponge natural product exiguamine A (3) have been prepared and evaluated for their ability to inhibit indoleamine 2,3-dioxygenase in vitro.