Seven new didemnins from the marine tunicate Trididemnum solidum

…, JG Stroh, DW Sullins, KL Rinehart

Index: Sakai, Ryuichi; Stroh, Justin G.; Sullins, David W.; Rinehart, Kenneth L. Journal of the American Chemical Society, 1995 , vol. 117, # 13 p. 3734 - 3748

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Citation Number: 64

Abstract

Abstract: Seven new didemnins-didemnins M (l), N (2), X (3), and Y (4), nordidemnin N (S), epididemnin AI (6), and acyclodidemnin A (7)-were isolated from an extract of the Caribbean tunicate Trididemnum solidum. The structures of these compounds were assigned, based on FABMS, high-field NMR data, and chemical degradation studies. Biological activities of these peptides are also described.