Simple Reduction of Heteroaromatic Esters to Alcohols Using a Sodium Borohydride–Methanol System

…, JS Mendonça, KC Paes, EL Fernandes…

Index: Boechat, Nubia; Da Costa, Jorge Carlos Santos; De Souza Mendonca, Jorge; Paes, Karla Ceodaro; Fernandes, Elisa Lopes; De Oliveira, Pedro Santos Mello; Vasconcelos, Thatyana Rocha Alves; De Souza, Marcus Vinicius Nora Synthetic Communications, 2005 , vol. 35, # 24 p. 3187 - 3190

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Citation Number: 8

Abstract

Abstract Some heteroaromatic esters were reduced to the corresponding alcohols by using a sodium borohydride–methanol system. The reduction was completed within 0.15–2.0 h in refluxing THF. The alcohol products were isolated after aqueous workup in moderate to excellent yield (48–97%).