2, 1-Benzothiazine 2, 2-dioxides. 1. Synthesis, structure, and analgesic activity of 1-R-4-hydroxy-2, 2-dioxo-1H-2λ6, 1-benzothiazine-3-carboxylic acid esters

…, LA Petrushova, SP Dzyubenko

Index: Ukrainets; Petrushova; Dzyubenko Chemistry of Heterocyclic Compounds, 2013 , vol. 49, # 9 p. 1378 - 1383 Khim. Geterotsikl. Soedin., 2013 , vol. 49, # 9 p. 1479 - 1485,7

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Citation Number: 25

Abstract

A preparative method for the synthesis of a series of 1-R-4-hydroxy-2, 2-dioxo-1H-2λ6, 1- benzothiazine-3-carboxylates has been developed. The special features of the steric structure for compounds of this class have been studied on the example of the 1-N-methyl