Biochemical and Biophysical Research Communications 1985-03-29

IHF stimulation of lambda cII gene expression is inhibited by the E. coli NusA protein.

S Peacock, H Weissbach

Index: Biochem. Biophys. Res. Commun. 127(3) , 1026-31, (1985)

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Abstract

The effects of E. coli proteins Integrative Host Factor (IHF) and NusA on the regulation of lambda cII gene expression are presented. As reported previously (Peacock et al. [1984] Proc. Natl. Acad. Sci. USA 81, 6009-6013), IHF stimulates the DNA-directed in vitro synthesis of cII protein or its first dipeptide, fMet-Val. Whereas NusA, by itself, has no effect on cII expression, the presence of NusA inhibits the IHF-mediated stimulation of cII synthesis.