Canadian Journal of Chemistry

N-(2-Diazo-3-oxoalkanoyl) glycine esters. I. Synthesis of 4-and 5-phenoxyl derivatives and isomerization of N-(2-diazo-3-oxo-3-phenylpropanoyl) glycine ethyl ester

JH Looker, JW Carpenter

Index: Looker,J.H.; Carpenter,J.W. Canadian Journal of Chemistry, 1967 , vol. 45, p. 1727 - 1734

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Citation Number: 11

Abstract

A new preparative procedure for N-(diazoacetyl) glycine ethyl ester is described. The interaction of N-(diazoacetyl) glycine ethyl ester with four phenoxyacetyl chlorides gives the 4-phenoxylderivatives of N-(2-diazo-3-oxobutanoyl) glycine ethyl ester, and with β-(o- methoxyphenoxy)-propionyl chloride yields N-[2-diazo-3-oxo-5-(o-methoxyphenoxy) pentanoyl] glycine ethyl ester. A general chromatographic procedure for separating N-(2- ...