Il Farmaco

New pyridine derivatives as potential antimicrobial agents

V Klimešová, M Svoboda, K Waisser, M Pour…

Index: Klimesova, Vera; Svoboda, Martin; Waisser, Karel; Pour, Milan; Kaustova, Jarmila Farmaco, 1999 , vol. 54, # 10 p. 666 - 672

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Citation Number: 70

Abstract

A set of pyridine derivatives bearing a substituted alkylthio chain or a piperidyl ring in position 2 or 4 were synthesized, and their antimycobacterial and antifugal activities were evaluated. Chemical structures were confirmed by IR and NMR data, and by elemental analysis. Minimum inhibitory concentrations (MIC) were used for the evaluation of microbiological activity in vitro. The compounds were moderately active against both ...