FEBS Letters 2012-11-30

ThePGM3gene encodes the major phosphoribomutase in the yeastSaccharomyces cerevisiae

Thomas Walther, Audrey Baylac, Ceren Alkim, Amélie Vax, Hélène Cordier, Jean Marie François

Index: FEBS Lett. 586(23) , 4114-8, (2012)

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Abstract

Highlights ► Pgm1, Pgm2, and Pgm3 accept glucose-1-P and ribose-1-P as substrates in vitro. ► Ribose-1-P is formed in vivo upon perturbation of energetic equilibrium. ► Ribose-1-P only hyper-accumulates in mutants carrying a deletion in PGM3. ► Pgm3 is the major phosphoribomutase in yeast.