Bioorganic & Medicinal Chemistry Letters 2005-10-01

3-(2-Aminoethyl)pyridine analogs as alpha4beta2 nicotinic cholinergic receptor ligands.

Małgorzata Dukat, Anna Ramunno, Rita Banzi, M Imad Damaj, Billy Martin, Richard A Glennon

Index: Bioorg. Med. Chem. Lett. 15 , 4308-12, (2005)

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Abstract

An examination of several 3-(2-aminoethyl)pyridine analogs suggests that they likely orient at alpha4beta2 nicotinic cholinergic receptors in a different fashion than their correspondingly substituted nicotine analogs.