Journal of Chemical Sciences

Activated anilide in heterocyclic synthesis: Synthesis of new hydrazo, dihydropyridazine, tetrahydropyridine, dihydropyridine and pyranopyridine derivatives

ISA Hafiz, MMM Ramiz, MA Elian

Index: Hafiz, Ibrahim Saad Abdel; Ramiz, Mahmoud Mohamed Mahfouz; Elian, Mohamed Ahmed Journal of Chemical Sciences, 2012 , vol. 124, # 3 p. 647 - 655

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Citation Number: 5

Abstract

Abstract A series of new hydrazo, dihydropyridazine, tetrahydropyridine, dihydropyridine and pyranopyridine derivatives with known biological activity have been prepared through the reactions of 3-oxo-3-phenyl-N-(pyridine-3-yl) propanamide 3 and enaminonitrile 17 with some electrophilic reagents, nucleophilic reagents, and aryl diazonium salts. The newly synthesized compounds were characterized by IR, 1 H NMR and mass spectral studies. ...