FEBS Letters 2014-05-02

Differential expression and anti-oxidant function of glutathione peroxidase 3 in mouse uterus during decidualization

Xiu Xu, Jing-Yu Leng, Fei Gao, Zhen-Ao Zhao, Wen-Bo Deng, Xiao-Huan Liang, Yi-Juan Zhang, Zhi-Rong Zhang, Ming Li, Ai-Guo Sha, Zeng-Ming Yang

Index: FEBS Lett. 588(9) , 1580-9, (2014)

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Abstract

• Gpx3 mRNA is strongly expressed in decidual cells from days 5 to 8 of pregnancy. • Progesterone stimulates Gpx3 expression through PR/HIF1α. • GPX3 may play a major role in reducing H2O2 during decidualization.