Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A concise synthesis of the 19-membered bis-lactone core 2b present in pateamine 1 using chiral pool starting materials and featuring an intramolecular Stille coupling reaction as a key stratagem, is described. ... A concise synthesis of the 19-membered bis-lactone portion of ...