Science of The Total Environment 2015-02-01

Identification of Triclosan-O-Sulfate and other transformation products of Triclosan formed by activated sludge.

Xijuan Chen, Mònica Escolà Casas, Jeppe Lund Nielsen, Reinhard Wimmer, Kai Bester

Index: Sci. Total Environ. 505 , 39-46, (2014)

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Abstract

Aerobic degradation experiments of Triclosan were performed in activated sludge to identify possible transformation products for this compound. During 7 days, the formation of biotransformation products such as 2,4-Dichlorophenol, 4-Chlorocatechol, 5-Hydroxy-Triclosan and other Monohydroxy-Triclosan derivatives as well as Dihydroxy-Triclosan-derivatives were observed. The structure of 5-Hydroxy-Triclosan was elucidated by NMR data for the first time in sludge degradation experiments. Additionally the production of a hitherto unknown transformation product in sludge, i.e., Triclosan-O-Sulfate was detected. During the incubations, the concentrations of this transformation product changed from zero to 330 μg L(-1). Based on the analysis of the biodegradation products, three types of reactions were identified: 1) chemical scission of ether bond to form phenols and catechols, 2) addition of OH moieties to the aromatic ring, and 3) adding of methyl or sulfate groups to the original hydroxyl group.Copyright © 2014 Elsevier B.V. All rights reserved.