Leaving group assistance in the La3+-catalyzed cleavage of dimethyl (o-methoxycarbonyl) aryl phosphate triesters in methanol

…, GE Garrett, AA Neverov, RS Brown

Index: Edwards, David R.; Neverov, Alexei A.; Brown, R. Stan Journal of the American Chemical Society, 2009 , vol. 131, p. 368 - 377

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Citation Number: 26

Abstract

The catalytic methanolysis of a series of dimethyl aryl phosphate triesters where the aryl groups contain an o-methoxycarbonyl (o-CO2Me) substituent (4a− i) was studied at 25° C in methanol containing La3+ at various concentrations and sspH. Determination of the second- order rate constant for La3+ 2-catalyzed cleavage of substrate 4a (dimethyl (o- methoxycarbonyl) phenyl phosphate) as a function of sspH was assessed in terms of a ...