Tetrahedron Letters

Direct coupling of nucleophiles with nitroaromatic compounds via fluoride-promoted oxidative nucleophilic aromatic substitution for hydrogen

I Huertas, I Gallardo, J Marquet

Index: Huertas, Inma; Gallardo, Iluminada; Marquet, Jordi Tetrahedron Letters, 2001 , vol. 42, # 20 p. 3439 - 3441

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Citation Number: 20

Abstract

Useful yields are achieved in the regioselective direct coupling of amines, amides, and ketones with m-dinitrobenzene, 1-nitronaphthalene, and 1, 3-dinitronaphthalene, through oxidatively activated nucleophilic aromatic substitution for hydrogen promoted by fluoride anions.