Bioorganic & Medicinal Chemistry Letters 2012-06-15

Coumarin–trioxane hybrids: Synthesis and evaluation as a new class of antimalarial scaffolds

Koneni V. Sashidhara, Abdhesh Kumar, Ranga Prasad Dodda, Naikade Niraj Krishna, Pooja Agarwal, Kumkum Srivastava, S.K. Puri

Index: Bioorg. Med. Chem. Lett. 22(12) , 3926-30, (2012)

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A series of novel coumarin–trioxane hybrids were synthesized and evaluated for antimalarial activity.

Structure	Name/CAS No.	Molecular Formula	Articles
	Sodium p-toluenesulfonate CAS:657-84-1	C₇H₇NaO₃S
	p-Toluenesulfonic acid monohydrate CAS:6192-52-5	C₇H₁₀O₄S
	Silver(1+) 4-methylbenzenesulfonate CAS:16836-95-6	C₇H₇AgO₃S
	ZINC(II) P-TOLUENESULFONATE CAS:13438-45-4	C₁₄H₁₄O₆S₂Zn