Optometry and Vision Science 2015-01-01

Corneal thickness differences between sexes after oxybuprocaine eye drops.

Pablo Fernandez-Garcia, Alejandro Cerviño, Laura Quiles-Guiñau, Cesar Albarran-Diego, Santiago Garcia-Lazaro, Juan A Sanchis-Gimeno

Index: Optom. Vis. Sci. 92(1) , 89-94, (2015)

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Abstract

We aimed to analyze the corneal thickness (CT) values of female and male subjects before and after instillation of oxybuprocaine 0.4% anesthetic eye drops.The CT of 30 female subjects and 28 male subjects was measured using scanning-slit corneal topography (Orbscan Topography System II, Orbscan, Inc, Salt Lake City, UT). Measurements were carried out before and 3 minutes after the instillation of oxybuprocaine 0.4% eye drops.The difference between the baseline values and those obtained after anesthesia ranged as follows: male subjects: central, -26 to +24 μm; superior, -24 to +23 μm; inferior, -19 to +20 μm; nasal, -25 to +30 μm; and temporal, -21 to +20 μm; female subjects: central, -16 to +24 μm; superior, -19 to +32 μm; inferior, -14 to +34 μm; nasal, -19 to +33 μm; and temporal, -36 to +16 μm. No significant differences were found in any corneal location in male subjects. The differences were significant at inferior (p = 0.001) and nasal (p = 0.011) corneal sites in female subjects.Oxybuprocaine anesthetic eye drops induce significant CT increases in female subjects but not in male subjects.