Design, synthesis and preliminary bioactivity studies of 1, 3, 4-thiadiazole hydroxamic acid derivatives as novel histone deacetylase inhibitors

P Guan, F Sun, X Hou, F Wang, F Yi, W Xu…

Index: Bioorganic and Medicinal Chemistry, , vol. 20, # 12 p. 3865 - 3872

Full Text: HTML

Citation Number: 30

Abstract

... Bioorganic & Medicinal Chemistry. ... a Department of Medicinal Chemistry, Key Laboratory ... b Department of Pharmacology, Shandong University, School of Medicine, Ji'nan, Shandong 250012, PR China. Received 25 February 2012, Revised 13 April 2012, Accepted 16 April 2012 ...