Atherosclerosis 2011-01-01

Alteration of volume-regulated chloride channel during macrophage-derived foam cell formation in atherosclerosis

Liang Hong, Zhi-Zhong Xie, Yan-Hua Du, Yong-Bo Tang, Jing Tao, Xiao-Fei Lv, Jia-Guo Zhou, Yong-Yuan Guan, Liang Hong, Zhi-Zhong Xie, Yan-Hua Du, Yong-Bo Tang, Jing Tao, Xiao-Fei Lv, Jia-Guo Zhou, Yong-Yuan Guan

Index: Atherosclerosis 216(1) , 59-66, (2011)

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Abstract

Objective Volume-regulated Cl − channel (VRCC) plays a critical role in regulation of a variety of physiological functions. However, little is known whether VRCC is involved in atherosclerosis. In this study, we investigated the functions of VRCC during foam cell formation in macrophages.