Natural product communications 2013-10-01

A new taraxerol derivative from the roots of Microcos tomentosa.

Sutin Kaennakam, Jirapast Sichaem, Suttira Khumkratok, Pongpun Siripong, Santi Tip-pyang

Index: Nat. Prod. Commun. 8(10) , 1371-2, (2013)

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Abstract

A new 3beta-O-vanilloyl-taraxerol, microcisin (1) and eight known compounds, 3beta-taraxerol acetate (2), 3beta-taraxerol (3), cholest-4-en-3-one (4), cholest-4-en-6beta-ol-3-one (5), beta-sitosterol (6), 7-hydroxycadalene (7), mellein (8) and vanillin (9), were isolated from the roots of Microcos tomentosa. The structures were determined by extensive analysis of their spectroscopic data. All isolated compounds were evaluated for their cytotoxicity against KB and HeLa cells.