Convenient synthesis of unsymmetrical aryl sulfides

F Bottino, R Fradullo, S Pappalardo

Index: Bottino, Francesco; Fradullo, Rosa; Pappalardo, Sebastiano Journal of Organic Chemistry, 1981 , vol. 46, # 13 p. 2793 - 2795

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Citation Number: 20

Abstract

On the other hand, owing to decreased strength of (4-nitropheny1) sulfenyl chloride as electrophilic agent: sulfides 20-23, bearing a nitro group in the para position, were prepared traditionally by nucleophilic condensation of p-nitrochlorobenzene with the appropriate potassium thiolate in refluxing ethanol (method C). The hitherto unreported 2, 4, 6- trimethoxythiophenol (26) and 3-chloro-2, 4, 6-trimethoxythiophenol (27) were prepared in