Polyfluoroalloxy phosphonic and phosphinic acid derivatives: I. 1-Hydroxy-2, 2, 2-trichloroethylphosphinates

VV Krutikova, VI Krutikov, AV Erkin

Index: Krutikova; Krutikov; Erkin Russian Journal of General Chemistry, 2010 , vol. 80, # 3 p. 428 - 433

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Abstract

Abstract Polyfluoroalkyl esters of 1-hydroxy-2, 2, 2-trichloroethylphosphonic and aryl (alkyl-) phosphinic acids exhibited antienzyme activity towards esterases of animal and microbial origin. A good correlation is observed between high antiesterase activity of the target compounds and their physicochemical parameters, characterizing their structure.