Microwave Irradiation–Assisted Amination of 2-Chloropyridine Derivatives with Amide Solvents

…, M do Carmo Carreiras, J Marco-Contelles

Index: Samadi, Abdelouahid; Silva, Daniel; Chioua, Mourad; Carreiras, Maria Do Carmo; Marco-Contelles, Jose Synthetic Communications, 2011 , vol. 41, # 19 p. 2859 - 2869

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Citation Number: 14

Abstract

Abstract A simple, quick, and high-yielding microwave-assisted synthesis of 2-(N, N- dimethyl) amine-and 2-aminopyridine derivatives is reported here for the first time in the reaction of 2-chloro substituted pyridines with amide solvents such as dimethylformamide or formamide, without transition-metal catalysts.