Tetrahedron

Synthesis of N, N-dimethyl-2, 4-dinitro-5-fluorobenzylamine and its reactions with amino acids and peptides

Z Liu, LM Sayre

Index: Liu, Zhongfa; Sayre, Lawrence M. Tetrahedron, 2004 , vol. 60, # 7 p. 1601 - 1610

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Citation Number: 4

Abstract

A practical synthesis is described for N, N-dimethyl-2, 4-dinitro-5-fluorobenzylamine (DMDNFB) and its-d6 analog as an alternative Sanger's reagent (DNFB), for purposes of amino acid derivatization detectable by positive mode electrospray ionization mass