Design, synthesis and antifungal activity of a novel water soluble prodrug of antifungal triazole

J Ohwada, M Tsukazaki, T Hayase, N Oikawa…

Index: Bioorganic and medicinal chemistry letters, , vol. 13, # 2 p. 191 - 196

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Citation Number: 40

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... Introduction. There is a high medical need for an injectable agent with a broad spectrum for the treatment of severe deep mycoses of hospitalized patients. ...

Design, synthesis and antifungal activity of a novel water s...

[Ohwada, Jun; Tsukazaki, Masao; Hayase, Tadakatsu; Oikawa, Nobuhiro; Isshiki, Yoshiaki; Fukuda, Hiroshi; Mizuguchi, Eisaku; Sakaitani, Masahiro; Shiratori, Yasuhiko; Yamazaki, Toshikazu; Ichihara, Shigeyasu; Umeda, Isao; Shimma, Nobuo Bioorganic and medicinal chemistry letters, 2003 , vol. 13, # 2 p. 191 - 196]

Substituted 1, 3-dihydro-2H-pyrrolo [2, 3-b] pyridin-2-ones ...

[Journal of Medicinal Chemistry, , vol. 33, # 10 p. 2697 - 2706]