Carboxyalkylation of ethylene diamine with β-chloropropionic acid. A new approach to ethylene diamine-N, N′-di-and ethylene diamine-N, N, N′, N′-tetrapropionic …

NV Tsirul'nikova, GP Chicherina…

Index: Tsirul'nikova; Chicherina; Fetisova Russian Journal of General Chemistry, 2010 , vol. 80, # 3 p. 543 - 544

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Abstract

Reactive ethylene diamine-N, N'-dipropionic acid II is used as initial reagent for incorporating into chosen structures of organic compounds to obtain a number of reagents containing ethylene diamine propionate moieties. However, the most obvious way to obtain acid II by nucleophilic substitution of chlorine in βchloropropionic acid by amino-group did not lead to desired results: By the reaction of β-chloropropionic acid with ethylene diamine ...