Synthesis and reactions of 2, 3-dihydro-5-aryl-5h, 6h-thiazolo [3, 2-b]-2, 4-diazafluorene-3, 6-diones of potential biological activities

…, A El-fotooh, G Hamman, SF Mohamed

Index: Ali, Mohamed I.; El-Fotooh, Abou; Hamman, G.; Mohamed, Salwa F. Phosphorus and Sulfur and the Related Elements, 1988 , vol. 39, p. 211 - 216

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Citation Number: 9

Abstract

Abstract 1, 2, 3, 4-Tetrahydro-l-aryl-3, 9-dioxo-2, 4-diazafluorenes (2) and 1, 2, 3, 4- tetrahydro-1-aryl-9-oxo-3-thi-oxo-2, 4-diazafluorenes (3) were newly synthesized. Compounds 3 reacted with chloroacetic acid, α-bromopropanoic acid, or B-bromopropanoic acid in the presence of fused sodium acetate and acetic anhydride to give 2, 3-dihydro-5- aryl-5H, 6H-thiazolo [3, 2-b] 2, 4-diazafluorene-3, 6-diones (4), 2-methyl-2, 3-dihydro-5- ...