Tetrahedron letters

Iridium-catalyzed oxidative esterification reaction of aliphatic aldehydes and olefinic alcohols with precoordination of the double bond of alcohols to iridium

S Kiyooka, M Ueno, E Ishii

Index: Kiyooka, Syun-Ichi; Ueno, Mahuyu; Ishii, Eri Tetrahedron Letters, 2005 , vol. 46, # 27 p. 4639 - 4642

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Citation Number: 34

Abstract

Iridium complexes are known to be effective for isomerization of allylic alcohols to aldehydes and ketones. 1 and 2 The transition metal-catalyzed isomerization of allylic alcohols is considered to proceed via the process involving a metal enolate, as depicted in Scheme 1, from the standpoint of the observation of tandem allylic alcohol isomerization aldol reaction. 3 and 4 On the basis of the mechanism, the possibility and the utilization of atom-economical generation of ...