Tetrahedron

1, 1-Diamino-2-nitroethylenes as excellent hydrogen bond donor organocatalysts in the Michael addition of carbon-based nucleophiles to β-nitrostyrenes

RC da Silva, GP da Silva, DP Sangi, JGM Pontes…

Index: Da Silva, Rodrigo C.; Da Silva, Gustavo P.; Sangi, Diego P.; Pontes, Joao G. De M.; Ferreira, Antonio G.; Correa, Arlene G.; Paixao, Marcio W. Tetrahedron, 2013 , vol. 69, # 43 p. 9007 - 9012

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Citation Number: 3

Abstract

Abstract A new class of hydrogen bond donor catalysts based on the 1, 1-diamino-2- nitroethylene scaffold has been introduced for the activation of trans-β-nitrostyrenes toward reactions with a range of carbon-based nucleophiles, affording the corresponding adducts in excellent yields. Importantly, this new set of organocatalysts is easily prepared from commercially available starting materials in mild reaction conditions.