In the attempt to prepare a new type of diphenhydramine derivatives, devoid of sedative side effects, we have synthesized a series of benzhydryloxyalkylpiperazines carrying a chain with a trivalent function (11). Surprisingly, some of the new compounds prepared, although structurally related to diphenhydramine, show novel, nonamphetaminic psychoanalpetic properties and lack pronounced peripheral anticholinergic activity. Chemistry. Most ...
![1-[2-chloroethoxy(phenyl)methyl]-4-methylbenzene Structure](https://image.chemsrc.com/caspic/009/53499-56-2.png)