Highly Diastereoselective Arylation of (S)-Mandelic Acid Enolate: Enantioselective Synthesis of Substituted (R)-3-Hydroxy-3-phenyloxindoles and (R)-Benzylic Acids …

S Barroso, G Blay, L Cardona, I Fernández…

Index: Langer, Peter; Holtz, Edith Synlett, 2003 , # 3 p. 402 - 404

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Citation Number: 38

Abstract

... optically active (S)-mandelic acid and pivalaldehyde with several o- and p-halonitrobenzenes proceeds ... of the dioxolanone moiety leads directly to enantiomerically pure (R)-3-hydroxy-3- phenyloxindoles. ... as terminal oxidant in the presence of pivalaldehyde and the Co(III)-Me 2 ...