1 I-Deoxydaunomycinone (Ib) has been synthesized via nucleophilic addition to the alicyclic part and directed lithiation at the aromatic part in the (+arene)tricarbonylchromium complexes of the hydronaphthalene derivatives. ... 11-deoxyadriamycin (2a), and 11-deoxycarminomycin (3a), are known to show a significant anticancer activity and less ... Tricarbonyl(v6-styrene)chromium was recognized as being equivalent to a Michael acceptor, in which nucleophilic addition ...
