Decarboethoxylation of aryl-substituted α-cyanoesters by the method of phase transfer catalysis

…, MY Polyakova, GM Sanzharova, OS Anisimova

Index: Glushkov; L'vov; Davydova; Kudinova; Polyakova; Sanzharova; Anisimova Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 3 p. 155 - 157

Full Text: HTML

Citation Number: 0

Abstract

Substituted arylacetoniwiles appear as intermediate products in the synthesis of some drugs. For example, 1-phenyl-1-cyanopropane (IIf) is involved in the synthesis of the broncholytic drug troventol, and 5-(N, N-diethylamino)-l-phenyl-1-cyanopentane (IIa) is used in the production of the antiarrhythmic drug nibentan [1].