Tetrahedron

One-pot synthesis of thiazolo [3, 4-a] quinoxalines and the related heterocyclic systems using 4-hydroxy-4-alkoxycarbonyl-3, 5-diaryl-2-aryliminothia (selena) zolidines …

…, NA Zhukova, AA Balandina, SV Kharlamov…

Index: Mamedov, Vakhid A.; Zhukova, Nataliya A.; Balandina, Alsu A.; Kharlamov, Sergey V.; Beschastnova, Tat'Yana N.; Rizvanov, Il'Dar Kh.; Latypov, Shamil K. Tetrahedron, 2012 , vol. 68, # 36 p. 7363 - 7373

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Abstract

An efficient and versatile one-step method for the synthesis of thiazolo [3, 4-a] quinoxalines and related new heterocyclic systems have been developed on the basis of a new strategy for the construction of the pyrazine ring system. The key step of the process involves the cascade annulation of the iminothiazolopyrazine system to benzene in the reaction of 4- hydroxy-3, 5-diaryl-2-phenyliminothiazolidines with 1, 2-diaminobenzenes. The use of ...