Samarium (II) iodide, in the presence of catalytic amounts of nickel (II) iodide, has been used to promote intramolecular conjugate additions of alkyl halides onto α, β-unsaturated lactones. This process has been shown to be applicable to a number of α, β-unsaturated lactones, including tetrasubstituted olefins, and has been demonstrated to be quite general for the formation of saturated bicyclic and tricyclic lactones. The method presented herein ...
![(1S,5S)-1-methyl-4-oxabicyclo[3.3.0]octan-3-one Structure](https://image.chemsrc.com/caspic/018/39778-83-1.png)
