The kinetic deuterium isotope effect as applied to metabolic deactivation of imatinib to the des-methyl metabolite, CGP74588

PW Manley, F Blasco, J Mestan, R Aichholz

Index: Bioorganic and Medicinal Chemistry, , vol. 21, # 11 p. 3231 - 3239

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Citation Number: 14

Abstract

... Bioorganic & Medicinal Chemistry. Volume 21, Issue 11, 1 June 2013, Pages 3231–3239. Cover image Cover image. The kinetic deuterium isotope effect as applied to metabolic deactivation of imatinib to the des-methyl metabolite, CGP74588. ...