Regiospecificity and stereospecificity of human UDP-glucuronosyltransferases in the glucuronidation of estriol, 16-epiestriol, 17-epiestriol, and 13-epiestradiol

N Sneitz, M Vahermo, J Mosorin, L Laakkonen…

Index: Drug Metabolism and Disposition, , vol. 41, # 3 p. 582 - 591

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Citation Number: 9

Abstract

... Centre for Drug Research (NS, JM ... The final DMSO concentration in the reaction was 10%, and the total reaction volume was 100 µl. ... These findings are expected to assist in predicting the glucuronidation of drugs that resemble estrogens or carry estrogen-like structural elements ...