Oxophilic synthetic receptors were designed and synthesized using a porphyrin scaffold, with the aim of constructing a preorganized complementary binding site for phenols and carbohydrates. We pursued three strategies for phenol recognition:(1) Lewis acid/Lewis base combinations serving as a hydrogen bond donor and acceptor for the OH group,(2) Lewis base/π-π stacking, targeting both the OH group and the aromatic moiety of phenols, ...
