Synthesis and biological characterization of 99mTc (I) tricarbonyl cysteine complex, a potential diagnostic for assessment of renal function

SH Park, BS Jang, KB Park

Index: Park, Sang Hyun; Jang, Beom Su; Park, Kyung Bae Journal of Labelled Compounds and Radiopharmaceuticals, 2005 , vol. 48, # 1 p. 63 - 73

Full Text: HTML

Citation Number: 5

Abstract

Abstract Cysteine containing three functional groups, ie a carboxyl, sulfhydryl, and amino group, has been labelled with 99m Tc (I) tricarbonyl precursor (2) in order to study the renal characteristics of the resulting 99m Tc (I) tricarbonyl cysteine (3) versus the reference 99m Tc-MAG 3 (1). The 99m Tc (I) tricarbonyl cysteine (3) was prepared in good yields and characterized by HPLC, eletrophoresis, and eletrospray mass spectrometry. The plasma ...