Synthesis, reactions and biological evaluation of some 1, 2, 4??triazine derivatives

…, DA Vanden Berghe, L Van Hoof

Index: Mansour; Eid; Hassan; Haemers; Pattyn; Vanden Berghe; Van Hoof Journal of Heterocyclic Chemistry, 1988 , vol. 25, # 1 p. 279 - 283

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Citation Number: 11

Abstract

Abstract 6-Substituted benzyl-4-phenyl-3-thioxo-2, 3, 4, 5-tetrahydro-1, 2, 4-triazin-5-ones 3a- d were prepared and converted into their corresponding 3-methylthio derivatives 4a-d. Reaction of compounds 4a-d with hydrazine hydrate gave the corresponding 4-amino-3- anilino-4, 5-dihydro-1, 2, 4-triazin-5-ones 5a-d. 6-Substituted benzyl-4-phenyl-2, 3, 4, 5- tetrahydro-1, 2, 4-triazin-3, 5-diones 9a-c were synthesized and allowed to react with ...