Synthesis and biological evaluation of some novel 2-mercaptobenzothiazoles carrying 1, 3, 4-oxadiazole, 1, 3, 4-thiadiazole and 1, 2, 4-triazole moieties

…, B Suresh, SS Kalsi, A Shinesh Antony

Index: Azam, M. Afzal; Suresh, Bhojraj; Kalsi, Sandip S.; Antony, A. Shinesh South African Journal of Chemistry, 2010 ,  vol. 63, p. 114 - 122

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Citation Number: 4

Abstract

ABSTRACT Several 2-mercaptobenzothiazole derivatives containing 1, 3, 4-oxadiazoles, 1, 2, 4-triazoles and 1, 3, 4-thiadiazoles at the second position were synthesized. Some of these synthesized compounds were evaluated for their in vivo analgesic, anti-inflammatory, acute toxicity and ulcerogenic actions. Some of the tested compounds showed significant analgesic and anti-inflammatory activities. Two of the compounds showed significant ...