Domino metathesis of 2-azanorbornenones: A new strategy for the enatioselective synthesis of 1-azabicyclic compounds

…, AG Csákÿ, R Medel, J Plumet

Index: Arjona, Odon; Csaky, Aurelio G.; Medel, Rocio; Plumet, Joaquin Journal of Organic Chemistry, 2002 , vol. 67, # 4 p. 1380 - 1383

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Citation Number: 60

Abstract

Alkaloids with pyrrolizidine 1, quinolizidine 2, pyrrolidinoazepine 3, and pyrrolidinoazocine 4 ring sistems have a wide and varied distribution in nature. These compounds display a broad range of interesting biological activities, and many of them serve as intermediates in the synthesis of more elaborated compounds. Accordingly, new strategies for the enantioselective synthesis of these azabicyclic skeletons continue to receive considerable attention. 1,2 In recent ...