Journal of the American Chemical Society

Studies in Prebiotic Synthesis. I. Aminomalononitrile and 4-Amino-5-cyanoimidazole1, 2

JP Ferris, LE Orgel

Index: Ferris,J.P.; Orgel,L.E. Journal of the American Chemical Society, 1966 , vol. 88, p. 3829 - 3831

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Citation Number: 101

Abstract

Abstract: The syntheses of aminomalononitrile and 4-amino-5-cyanoimidazole are described. Acid anhydrides react with aminomalononitrile to yield oxazoles. Aminomalononitrile is converted to diaminomaleonitrile by cyanide and to 4-amino-5- cyanoimidazole by formamidine. Adenine results from the reaction of 4-amino-5- cyanoimidazole with formamidine. 4-Cyano-5-aminooxazole is converted to 7- ...