Synthesis of Some New 4-(2-Chloropyridin-4-yl)-N-Aryl-1, 3-Thiazol-2-Amine Derivatives as Possible Antifungal and Antibacterial Agents

B Narayana, KK Vijaya Raj, BV Ashalatha…

Index: Narayana; Vijaya Raj; Ashalatha; Kumari, N. Suchetha Phosphorus, Sulfur and Silicon and the Related Elements, 2007 , vol. 182, # 1 p. 7 - 14

Full Text: HTML

Citation Number: 4

Abstract

Novel 4-(2-chloropyridin-4-yl)-N-aryl-1, 3-thiazol-2-amines have been prepared by reacting (4-bromoacetyl)-2-chloropyridine with thiourea and substituted thioureas. The newly synthesized compounds have been characterized by analytical and spectral data. All the compounds have been screened for their antifungal and antibacterial activities. Almost all the compounds were found to possess excellent antifungal and antibacterial activities.