Short and efficient syntheses of coriolic acid

AVR Rao, SP Reddy, ER Reddy

Index: Rao, A. V. Rama; Reddy, S. Pulla; Reddy, E. Rajarathnam Journal of Organic Chemistry, 1986 ,  vol. 51,  # 22  p. 4158 - 4159

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Citation Number: 27

Abstract

Coriolic acid (1)'belonging to a family of oxyoctadecadienoate congeners commonly found in vegetable oils was isolated from bovine heart mitochondria and shown to possess unique calcium-specific ionophoric activity. 2 Recently 1 was also isolated from Fukuyuki (Oryza satiue L.) and demonstrated to act as self-defensive substance against rice blast di~ ease.~ Compound 1 is also present in sera of patients with familial Mediterranean fever (FMF) ...