Succinylacetone oxidation by oxygen/peroxynitrite: A possible source of reactive intermediates in hereditary tyrosinemia type I

LO Royer, FS Knudsen, MA de Oliveira…

Index: Adam, Waldemar; Catalani, Luiz H.; Saha-Moeller, Chantu R.; Will, Bernd Synthesis, 1989 ,  # 2  p. 121 - 123

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Citation Number: 6

Abstract

... A nine line spectrum [a N = 1.63 mT; a H = 0.99 mT (2H)] was observed upon exposure of SA to peroxynitrite at pH 7.2 in the presence of MNP (Figure 7). This spectrum can be assigned to a • CH 2 R radical, as predicted by the reaction mechanism shown in ...